Astrocytic Glutamate Transporter 1 (GLT1) Deficiency Reduces Anxiety- and Depression-Like Behaviors in Mice
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چکیده
منابع مشابه
NMDA glutamate receptor inhibition in the dorsal hippocampus reduced the maintenance of electric foot shock stress -induced anxiety and depression like behaviors in mice
Introduction: In the present study, the effect of inhibition of glutamate NMDA receptors located in the dorsal hippocampus on the maintenance of anxiety and depression like behaviors induced by electric foot shock stress was investigated. Materials and Methods: NMARI male mice were divided into two categories. The first category received electro foot shock for 30 minutes after injection of mema...
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L-histidine is one of the essential amino acids for humans, and it plays a critical role as a component of proteins. L-histidine is also important as a precursor of histamine. Brain histamine is synthesized from L-histidine in the presence of histidine decarboxylase, which is expressed in histamine neurons. In the present study, we aimed to elucidate the importance of dietary L-histidine as a p...
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Background CD226 is a cell surface adhesion molecule expressed in the immune system and central nervous system. Although the role of CD226 in the function of immune cells has been well studied, there has been no report on the potential functional significance of CD226 in neural cells. Methods We investigated the role of CD226 on the cognitive function and behaviors using CD226 knockout (CD226...
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ژورنال
عنوان ژورنال: Frontiers in Behavioral Neuroscience
سال: 2020
ISSN: 1662-5153
DOI: 10.3389/fnbeh.2020.00057